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| Model | Edge | TrueBeam / VitalBeam | Trilogy | Clinac iX | Clinac <2100C / 2100CD | Clinac 21EX |
| Other Variations | Edge Radiosurgery System | TrueBeam STX, SVC (Small Vault Configuration), VitalBeam | Trilogy STX, Novalis, Trilogy Silhouette | iX Silhouette, DMX, DHX, 2100C, CX | 2100C, 2300C/D, 2100C/D | 21EX Silhouette, 2100C, 2100C/D 23EX |
| Years Manufactured | 2013 & newer | 2010 & newer | 2005 & newer | 2004 - current | 1987-2007 | 1998-2006 |
| Power Source | Klystron | Klystron | Klystron | Klystron | Klystron | Klystron |
| Photon Energy Configuration | 6&10/15/18 | 6&10/15/18 | 6&10/15/18 | 6&10/15/18 | 6&10/15/18 | 6&10/15/18 |
| Electron Energies | Yes | Yes | Yes | Yes | Yes | Yes |
| Multi-Leaf Collimator (MLC)** | 120 Leaf HDMLC
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120 MLC
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120 MLC
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80 MLC (Field size 40x40cm); 120 MLC
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80 MLC (Field size 40x40cm); 120 MLC
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80 MLC (Field size 40x40cm); 120 MLC
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| Portal Imager(EPID)** | aS1000 | aS1000 | aS1000 | aS500, aS1000 | LC250, aS500, aS1000 (optional) | LC250, aS500, aS1000 (optional) |
| Treatment Delivery | 3D, IMRT, SRS/SBRT | 3D, IMRT, RapidArc, SRS/SBRT | 3D, IMRT, RapidArc, SRS/SBRT | 3D, IMRT, RapidArc, SRS/SBRT (optional) | 3D, IMRT, SRS/SBRT (optional) | 3D, IMRT, SRS/SBRT (optional) |
| KV Imaging for IGRT** | OBI | OBI | OBI | OBI (optional) | OBI (optional) | OBI (optional) |
| Cone-Beam CT | Yes | Yes | Yes | Only with OBI | Only with OBI | Only with OBI |
| VMAT | Yes | Yes | Yes | Only with OBI | Only with OBI | Only with OBI |
| Stereotactic Radiosurgery** | Integrated with Linear Accelerator (LINAC) | Integrated with Linear Accelerator (LINAC) | Integrated with Linear Accelerator (LINAC) | Optional Cones or mMLC | Optional Cones or mMLC | Optional Cones or mMLC |
| Treatment Couch | PerfectPitch | Exact IGRT | Exact IGRT | Exact, Exact IGRT (optional) | ETR, Exact (optional) | Exact |
| Silhouette Option Available for Smaller Room Size | Yes | Yes | Yes | Yes | Yes | |
| Market Demand*** |  |
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| Pros | Designed for stereotactic radiosurgery (SRS) Intracranial radiosurgery package 2400 mu/min dose rate | Fully integrates gating, imaging, and arc therapy High level of precision for SRS/SBRT, higher dose rate, Rapid Arc is standard | Great for SRS and SBRT Offers all the features of an iX Tighter isocenter than iX Service/maintenance costs lower than TrueBeam Very stable platform | Varian’s workhorse machine; very reliable Come with a variety of upgrades & options | Similar to 21EX and iX | Essentially the same as a 21/23iX for much lower cost Lots of available systems, many with low beam hours Great value system for an affordable price |
| Cons | So new that none exist in secondary market | Expensive, although pricing has decreased Service/maintenance contracts are expensive Some parts are very expensive to replace So new that few exist in secondary market | Not many available in the secondary market | Some may not have all the desired upgrades Limited inventory in secondary (used) equipment market | Similar to 21EX and 21iX | Installation costs are similar to newer models Some may not have all the desired options |
*Data shown here may not be accurate and is based on equipment seen in the secondary market. See manufacturers for exact data.
**Similar devices are manufactured by vendors other than the linear accelerator manufacturer.
***Five stars indicate that the resale demand for like systems is high, and used equipment will therefore command a higher price. Few stars indicate that the resale demand is lower, and prices for used equipment is lower. One star indicates very little, if any, demand currently exists.
